LTP and LTD An Embarrassment of Riches
نویسندگان
چکیده
LTP and LTD, the long-term potentiation and depression of excitatory synaptic transmission, are widespread phenomena expressed at possibly every excitatory synapse in the mammalian brain. It is now clear that "LTP" and "LTD" are not unitary phenomena. Their mechanisms vary depending on the synapses and circuits in which they operate. Here we review those forms of LTP and LTD for which mechanisms have been most firmly established. Examples are provided that show how these mechanisms can contribute to experience-dependent modifications of brain function.
منابع مشابه
ReviewLTP and LTD : An Embarrassment of Riches
control their firing properties, neurons can vary in terms of the specific forms of LTP and LTD they express. Palo Alto, California 94304 2 Howard Hughes Medical Institute and the We would also argue that it is no longer particularly productive to debate the generic question of whether Picower Center for Learning and Memory Massachusetts Institute of Technology LTP and LTD are cellular/synaptic...
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ورودعنوان ژورنال:
- Neuron
دوره 44 شماره
صفحات -
تاریخ انتشار 2004